The NNLM All of Us Program Center (NAPC) coordinates engagement and training activities offered by NNLM in support of the NIH All of Us Research Program (All of Us), a large, multi-faceted research initiative seeking to collect biomedical data from one million people across the United States, to support precision medicine by diversifying the data available for biomedical research.

The NNLM National Center for Data Services (NCDS) coordinates with other NNLM Regions, Offices, and Centers to provide training and resources to increase data science capacity among information professionals, in alignment with the NLM strategic plan.

The NNLM National Evaluation Center (NEC) provides innovative evaluation frameworks and evidence-based evaluation tools and practices to NNLM. The NEC is located at the Galter Health Sciences Library and Learning Center, Northwestern University, Feinberg School of Medicine in Chicago.